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Ketoconazole also may reduce the elimination of some statins for example, simvastatin Zocor leading to an increase in the blood levels of statins and increasing the risk of side effects such as rhabdomyolysis severe muscle injury. This occurred when ketoconazole was administered at doses higher than 10 mg kg higher than. cheap ketoconazole dalsi den Talk to your doctor about the possible risks of using this drug for your condition. Review of their clinical pharmacology and therapeutic applications.